Activity Number
Overview and Learning Objectives
Classroom Practice
Central Concepts
Textbook References
Activity Credits

DNA Hybridization (Plain Model)

Interactive model, with minimal support

Activity Screenshot

Go To Activity

Follow the link above to start or download this activity.

This Activity Requires:

      Test your system to see if it meets the requirements

Important! If you cannot launch anything from this database, please follow the step-by-step instructions on the software page.

Please Note: Many models are linked to directly from within the database. When an activity employs our scripting language, Pedagogica, as do some of the "guided" activities, the initial download may take several minutes. Subsequent activities will not take a long time. See this page for further instructions.

Overview and Learning Objectives

Students can watch molecular probes.

This is a model without activity support.

return to top

Classroom Practice

A full activity can be found in the database as DNA Hybridization: Southern Blot (

return to top

Central Concepts

Key Concept:

Probes made of nucleotide sequences can bind to target sequences.

Additional Related Concepts


  • Genetics

Molecular Biology

  • Base pairs
  • Coding
  • Complementarity
  • DNA
  • Nucleotide

return to top

Textbook References

  • Biology (Prentice-Hall) New York Edition - Chapter 12: DNA and RNA
  • Biology: Concepts and Connections (Pearson) 5th Edition - Chapter 12: DNA Technology and the Human Genome
  • Biology: Exploring Life - Chapter 11: DNA and the Language of Life

return to top

Activity Credits

Created by CC Project: Molecular Workbench using Molecular Workbench

return to top

NSF Logo
These materials are based upon work supported
by the National Science Foundation under grant numbers
9980620, ESI-0242701, EIA-0219345, DUE-0402553, and 0628181.

Any opinions, findings, and conclusions or recommendations expressed in this
material are those of the author(s) and do not necessarily reflect
the views of the National Science Foundation.